Update 06/11/26: An additional method for using Case It v705 on Macs is now available, via a virtual machine (UTM) running Windows 11 Pro. This method requires an Apple Silicon (M-series) Mac and does involve some installation time, but it will work on future versions of the Mac OS (OS28 and beyond). Case It v705 runs very fast this way, at near-native speed. See the Download page for links and detailed instructions.
Case It v705 performs common laboratory procedures on any DNA or protein sequence and can be downloaded free of charge for educational use. Sequences included with the download enable students to analyze a variety of cases with a focus on genetic and infectious diseases. The CRISPR exercise enables students to learn basic molecular biology techniques while recreating and analyzing Nobel Prize-winning research experiments. The first study to successfully use CRISPR to treat a genetic condition is analyzed in the ATTR exercise. The mRNA exercise enables students to recreate Nobel Prize-winning experiments that resulted in the development of mRNA vaccines.