Action Potential Experiments

An online version of the Action Potential Experiments simulation is available. The original  simulation was published by the BioQUEST Curriculum Consortium, and is still available from this link at the BioQUEST site. That version runs only on Windows XP and earlier, and Mac OS9. However, using video screen capture technology, the online version will run on any device.

Action Potential Experiments is a demonstration/simulation laboratory for neurophysiology based on the “sodium theory” as originally formulated and tested by A. L. Hodgkin and his colleagues. It includes simulations of the original experiments of Hodgkins and Huxley, and of the classic voltage clamp and patch clamp experiments, as well as an animated illustration of the “sodium theory” explanation of Nernst potentials for potassium and sodium ions. The student can perform simple ion concentration experiments to test the predictions of the theory, similar to the experiments originally performed by Hodgkin and Huxley.

Check it out at https://www.caseitproject.org/action-potential-experiments/.