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Case It!

Simulations for Case-Based Learning in Molecular Biology

  • MOBILE
    • What is Case It Mobile?
    • Sickle cell disease mobile
    • —-explore SCD mutation
    • Huntington’s disease mobile
    • —- HD BLAST analysis
    • DMD mobile
    • Alzheimer’s disease mobile
    • —-explore AD mutation
    • PKU mobile
    • —-explore PKU mutation
    • Cystic fibrosis mobile
    • —-explore CF mutation
    • Tay-Sachs disease mobile
    • MRSA mobile
    • CRISPR Part 4 mobile
  • What is Case It?
    • Project overview
    • Overview of Case It v705
    • Suggestions for class use
    • About
      • Credits
      • Publications
      • Contact
        • SNP microarrays
  • Tutorials
    • Case It v705 Tutorials page
    • Case It YouTube Channel
      • Overview of the Case It interface
      • PCR: primers, digestion and electrophoresis – CF example
      • Part 1: Digestion and DNA electrophoresis – CRISPR example
      • Part 2: Digestion and DNA electrophoresis – virtual tools
      • ELISA, Western blots and RT-qPCR
      • Southern and Dot Blots – genetic disease example
      • Quantitative (Real Time) PCR – honeybee example
      • Bioinformatics tree building – HIV example
      • SNP microarrays
      • Expression microarrays
  • Cases
    • All cases
    • Human genetic diseases
      • Introduction
      • Alzheimer’s disease
      • Cystic fibrosis
      • Duchenne muscular dystrophy
      • Huntington’s disease
      • Phenylketonuria (PKU)
      • Tay-Sachs disease
      • Fragile X syndrome
      • Sickle cell disease
    • Infectious diseases
      • Introduction
      • Ebola
      • HIV / AIDS
      • Influenze – human
      • Influenze – avian
      • Malaria
      • Methicillin-resistant Staphylococcus aureus (MRSA)
      • Salmonella
      • Severe Acute Respiratory Syndrome (SARS)
      • Sexually-transmitted infections
      • Vibrio (cholera)
      • West Nile virus
    • Cancer
      • Breast cancer susceptibility
      • Colon cancer
      • Prostate cancer – microarray
      • Melanoma – microarray
      • Breast cancer – microarray
    • CRISPR/MRNA
      • CRISPR Nobel Prize exercise
      • CRISPR ATTR exercise
      • MRNA Nobel Prize exercise
    • Microarrays
      • Overview
      • SNP
        • Cardiac disease
        • HIV resistance
        • Prostate cancer
        • Pharmacogenomics
      • Expression
        • Breast cancer
        • Herpes
        • Melanoma
    • Honey bee ecology
      • Pesticides and viruses
      • Mites and virus diversity
      • Hives and mites
      • Hive DNA qPCR
    • Plant cases
      • Bt corn
      • Cannabis Case A
      • Cannabis Case B
    • Forensics
      • Murder case
      • Thomas Jefferson case
    • Phylogenetics
      • Primate relationships
      • Squirrel taxonomy
      • Color vision in primates (research project)
    • Simulation of wet labs
      • Lambda DNA digestion
      • Phage DNA mapping
      • Human Alu detection
  • Download
    • Windows and Mac versions
  • CRISPR / mRNA / Action Potential
    • CRISPR (2020 Nobel Prize)
    • CRISPR ATTR exercise
    • mRNA (2023 Nobel Prize)
    • Action Potential Experiments (1963 Nobel Prize)

Examples

Examples of strategies for using Case It in classes

 

Here are a few examples of how we have used various features of  Case It in classes.  We encourage users to share their own ideas by posting them to the Forum.

 

General suggestions for class use

 

Genetic disease case with online role playing (Huntington’s disease)
HIV case with introduction to bioinformatics
Open-ended projects using influenza virus sequences
Design new cases

RESOURCES

CASE IT SOFTWARE

  • Overview
  • Case It v705 Tutorials
  • Case It YouTube channel
  • Download software

RELATED RESOURCES

  • Case descriptions
  • Suggestions for class use
  • AAAS Science Prize article
  • Analyze Pioneering CRISPR Research Experiments
  • Analyze Pioneering mRNA vaccine experiments
  • Action Potential Experiments online
  • Case It Mobile

ACKNOWLEDGEMENTS

Case It has been supported by grants from the National Science Foundation with additional support from the University of Wisconsin – River Falls.
(2026 NCAA Division III Football National Champions!)

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